Alarming cancer symptoms highlighted by popular actor's early death

→ James Van Der Beek’s death highlights alarming colon cancer rise in younger adults

→ Daily coffee habit may play role in dementia risk, study finds

→ ‘Doormat Mom’ says she was ‘blindsided’ when her daughter cut her off

 → Popular weight-loss drugs linked to rare nutrition-related disease, researchers warn

→ Big mistake to legalize marijuana? Health experts warn of ‘worse outcomes'

→ People with a certain BMI may be more prone to deadly infections

→ Common household plant could hold a secret to fighting Alzheimer's disease

→ Fast-food chain to ban all microwaves from restaurants to 'improve quality'

→ Can TrumpRx help you save money on prescription drugs?

→ Brain training sessions found to reduce dementia risk for decades

→ Common sleep aid could be quietly interfering with your rest, study suggests

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"The pain of being cut off — it’s a pain you can’t describe unless you feel it." 

→ Laura Wellington, a woman in Connecticut known on social media as "Doormat Mom," shared her story of parent-child estrangement with Fox News Digital.

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Brain training sessions found to reduce dementia risk in decades-long study

An update on a decades-long investigation has suggested that brain training can lower the risk of dementia.

The Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) study, which began in the late 1990s with nearly 3,000 older adults, evaluated how brain training impacts thinking and memory.

The participants, who ranged in age from 65 to 94 at the start of the trial, were randomly placed in groups for 10 training sessions in memory, reasoning, or speed of processing. The 60- to 75-minute sessions were conducted over six weeks.

ALZHEIMER’S DISEASE COULD BE REVERSED BY RESTORING BRAIN BALANCE, STUDY SUGGESTS

Another randomly selected group received "booster" training 11 months and 35 months after the initial session.

A recent follow-up study found that the participants who received cognitive speed training, in addition to follow-up training several years later, were 25% less likely to receive a dementia diagnosis over the next two decades.

This is one of the first results from the trial to demonstrate that "any intervention, whether it is cognitive training, brain games, physical exercise, diet or drugs, can lower the incidence of Alzheimer's disease and related dementias," according to principal researchers at the University of Florida College of Public Health and Health Professions.

The findings were published in the journal Alzheimer's & Dementia: Translational Research and Clinical Interventions.

ALZHEIMER’S PILL COULD REDUCE BRAIN DECLINE IN SOME HIGH-RISK PATIENTS, TRIAL SUGGESTS

Participants who had the "greatest advantage" underwent a maximum of 18 training sessions over three years, according to researcher Michael Marsiske, PhD, a professor and interim co-chair of the Department of Clinical and Health Psychology at UF Health.

Marsiske told Fox News Digital that he was "absolutely surprised" by these findings.

"Our initial findings had shown benefits of several training arms up to 10 years after training, with participants reporting less impairment in tasks of daily living and fewer motor vehicle crashes," the researcher said. "These 20-year findings strongly suggest that engagement in cognitive training does no harm and may confer substantial benefit."

Speed training requires the participants to process visual information on a computer screen and "make quick decisions."

"As participants' speed and accuracy improved, the training got progressively more difficult," the UF Health press release stated. "Speed training may cause physical changes to the brain, leading to new and stronger connections between brain networks."

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Participants reported benefits after five years, including less difficulty performing tasks like cooking, taking medication and managing finances. After 10 years, those who were trained in reasoning and speed of processing "maintained cognitive improvement," the researchers shared.

Based on the latest 20-year results, the team plans to launch follow-up trials to explore how older adults can benefit from pairing cognitive training with lifestyle habits like physical activity, diet improvements and blood pressure management.

"I'm most excited about the ability to merge real-world data, like Medicare records, with a clinical trial like ours," Marsiske shared with Fox News Digital.

This study was funded by the National Institute on Aging and the National Institute of Nursing Research. Fox News Digital reached out to UF Health for comment.

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Other recent research has attempted to link certain lifestyle changes and exercises to reduced dementia risk. A new study, published in the journal JMIR Serious Games, found that playing certain games on a smartphone can improve attention and memory.

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Dr. Daniel Amen, psychiatrist and founder of Amen Clinics, previously commented on this method of brain training, noting that it’s "critical" to continue learning and to challenge the brain, but that it's important to set boundaries.

"If you can be disciplined, word games, for example, or Sudoku games … can be helpful and have been shown to increase memory," he told Fox News Digital.

"New learning is a very important, critical strategy to decrease aging," Amen went on. "You should be spending 15 minutes a day learning something new that you don’t know … whether it's a language, a musical instrument, a new gardening technique or a new technique in cooking."

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Popular weight-loss drugs linked to rare 'pirate disease,' researchers warn

Researchers in Australia are raising flags about GLP-1 weight-loss medications potentially raising the risk of a rare disease.

Scurvy — historically called a "pirate disease" due to long voyages at sea without nutritious food — is caused by a lack of vitamin C. If left untreated, scurvy can cause severe symptoms, according to Cleveland Clinic.

Those symptoms include anemia, loosened teeth that may fall out, bleeding under the skin, bruising, swollen legs, rough and scaly skin, dry and brittle hair that coils, and the re-opening of wounds that do not heal. Swollen, bleeding gums are another common result.

NEW WEIGHT-LOSS SHOT SHOWS MAJOR FAT REDUCTION, BUT EXPERTS URGE CAUTION

The disease could surface as the result of not properly providing the body with nutrient-rich foods, leading to malnourishment. New research suggests that GLP-1 drug users may be at greater risk.

A systematic review by the Hunter Medical Research Institute in Australia found that although diabetes and obesity medications support significant improvements in weight loss, clinical trials have "failed to report what people are actually eating while taking them."

"A reduction in body weight does not automatically mean the person is well-nourished or healthy," Clare Collins, laureate professor of nutrition and dietetics at The University of Newcastle, Australia, wrote in a press release statement. "Nutrition plays a critical role in health, and right now it’s largely missing from the evidence."

These findings raise "major concerns about the risk of malnutrition, including macro and micro-nutrient deficiencies, with adverse metabolic and nutritional effects being reported," Collins told Fox News Digital.

OBESITY EXPERT REVEALS THE BEST WAY TO DECIDE IF GLP-1S ARE RIGHT FOR YOU

Certain GLP-1 and GIP medications have a "major impact" on appetite and satiety, which leads to overall reduced food intake, according to the researcher.

"While this mechanism drives weight loss, it also increases the risk of inadequate protein, fiber, vitamin and mineral intakes if diet quality and nutritional adequacy are not carefully monitored," she cautioned.

British pop singer Robbie Williams was diagnosed with scurvy in 2025, previously sharing with The Mirror that he experienced symptoms of the "17th-century pirate disease" after he’d been taking "something like Ozempic."

Collins noted that nutrient deficiencies are "not specific" to scurvy.

"There are other nutrients that, if not consumed in adequate amounts, can lead to deficiencies," she said.

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Iron deficiency can cause anemia, for example, and vitamin B1 deficiency leads to beriberi (a disease that can damage the nerves and heart) and Wernicke’s encephalopathy (a potentially life-threatening brain disorder), according to Collins.

For GLP-1 users who are losing weight quickly, Collins emphasized the importance of an adequate intake of nutrients, vitamins and minerals.

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"The signs can be missed because they overlap initially with side effects of the medications, including fatigue, lethargy, nausea, poor appetite and irritability," she said.

To ensure proper nutrition, Collins recommends seeking professional help from an accredited dietitian.

"It is challenging to assess whether your nutrient intake is adequate by yourself," she said. "People may also require a specific multivitamin or mineral supplement, along with medical nutrition therapy support."

Future clinical trials should include "validated dietary assessment tools" and "transparent reporting of food and nutrient intakes," Collins suggested.

"This will help improve the nutrition-related health and wellbeing outcomes for individuals prescribed these medications, while supporting adherence and long-term health," she said.

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"We’re calling for greater attention to nutrition when these medications are being prescribed in order to avoid malnutrition risk."

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James Van Der Beek’s death highlights alarming colon cancer rise in younger adults

Following actor James Van Der Beek's death after a 2½-year battle with colon cancer, experts are warning of the disease's prevalence among younger people.

The "Dawson’s Creek" star announced his stage 3 colon cancer diagnosis in November 2024, although he was officially diagnosed in August 2023 after a colonoscopy.

In an August 2025 feature with Healthline, Van Der Beek revealed the first warning sign of colon cancer was a change in bowel movements, which he chalked up to an effect of drinking coffee.

JAMES VAN DER BEEK, ‘DAWSON’S CREEK' AND ‘VARSITY BLUES’ STAR, DEAD AT 48

"Before my diagnosis, I didn’t know much about colorectal cancer," the actor said. "I didn’t even realize the screening age [had] dropped to 45; I thought it was still 50."

Recent research has shown an alarming rise in colorectal cancer (CRC) cases among younger individuals.

The American Cancer Society published evidence in January that colorectal cancer is now officially the leading cause of cancer-related death among men and women 50 and younger.

COLORECTAL CANCER NOW DEADLIEST TYPE FOR CERTAIN GROUP OF AMERICANS, STUDY FINDS

This is a significant increase from the 1990s, when it was the fifth deadliest.

While overall cancer deaths have been on the decline for this age group since 1990, dropping by about 44% combined, CRC is the only major cancer that has seen a spike in mortality for those under 50 during that time period, the researchers noted.

Dr. Aparna Parikh, medical director of the Center for Young Adult Colorectal Cancer at the Mass General Cancer Center, who is not affiliated with the ACS, shared that experts don’t "entirely understand why" cases are on the rise.

"But it seems to be an interplay of a person’s risk factors, overall makeup and early exposures," she previously told Fox News Digital. "The exposures include dietary exposures, environmental exposures and possible antibiotic exposures, as well as lifestyle factors in the right host."

ACTOR WITH COLORECTAL CANCER SHARES SIMPLE SIGN THAT HE IGNORED: ‘I HAD NO IDEA’

Another recent ACS study discovered that drinking heavily and consistently over an adult’s lifetime could lead to a higher risk of colorectal cancer.

Other primary risk factors include family history, obesity, smoking, a diet high in red and processed meats, inflammatory bowel disease, and a personal history or family history of polyps.

In a Thursday appearance on "America’s Newsroom," Fox News senior medical analyst Dr. Marc Siegel commented on the rise of CRC among younger individuals.

"There is a genetic issue, but there’s also ultraprocessed foods — a new study out of Mass General shows a high diet in that… [you’re] 45% more likely to have colon cancer," he said.

COLORECTAL CANCER MAY CAUSE THESE 4 HIDDEN WARNING SIGNS, EXPERTS SAY

There is also a 30% increase in risk with a diet higher in processed meats, like hot dogs, and a 20% increase with diets higher in red meat, according to Siegel.

"These are the villains here," he said. "That, plus genetics. And I’m urging everyone out there — change the age for screening to 45, or even below if you have risk factors. That’s really key."

While there may be no symptoms of CRC before diagnosis, especially in the early stages, certain symptoms should not be overlooked, experts say.

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Dr. Eitan Friedman, Ph.D., an oncologist and founder of The Suzanne Levy-Gertner Oncogenetics Unit at the Sheba Medical Center in Israel, confirmed that changes in bowel habits are the primary red flag that should raise the suspicion of colorectal cancer.

Other symptoms include fatigue as a result of anemia, a change in bowel movements, stomach pain or abdominal discomfort, rectal bleeding or blood in stool, weakness and unexplained weight loss, Friedman, who did not treat Van Der Beek, told Fox News Digital.

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Dr. Erica Barnell, Ph.D., a physician-scientist at Washington University School of Medicine — and co-founder and chief medical officer at Geneoscopy — noted that the actor's experience of having no "glaring" signs is common.

"Many colorectal cancers develop silently, without obvious symptoms," Barnell, who also did not treat Van Der Beek, told Fox News Digital. "By the time symptoms appear, the disease may already be advanced."

The key to getting ahead of colorectal cancer is early detection, according to experts.

"Colonoscopy at age 45 onwards, at five- to 10-year intervals, has been shown to lead to early detection of polyps that have the potential to become malignant, and to allow for their removal as an effective means of minimizing the risk of malignant transformation," Friedman said.

Unfortunately, Barnell noted, "screening compliance in the U.S. remains below national targets, and gaps are widest in rural, low-income and minority communities."

"Most people don’t like talking about bowel habits, but paying attention to changes can save your life," the doctor said. "Screening gives us the chance to find problems early — often before you feel sick — and that can make all the difference."

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Siegel also pushed for colonoscopies as the best method to screen for CRC, especially if a polyp is detected and removed before turning into cancer.

Fox News Digital’s Christina Dugan Ramirez contributed to this report.

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Common household plant could hold key to fighting Alzheimer's disease

A potential weapon against Alzheimer’s disease could be hidden in aloe vera, scientists recently uncovered.

Aloe vera, a rubbery green plant, may be best known for its skin-soothing qualities, but a study published in Current Pharmaceutical Analysis suggests that key chemicals within the plant could interact with enzymes involved in Alzheimer’s disease, hinting at a new approach to disrupting cognitive breakdown.

A chemical messenger in the brain called acetylcholine, which helps nerve cells communicate, is reduced in Alzheimer’s patients, contributing to memory loss and cognitive decline, according to the study press release.

SCIENTISTS REVEAL THE ONE PRACTICE THAT COULD PREVENT DEMENTIA AS YOU AGE

Two enzymes in the brain (cholinesterase and butyrylcholinesterase) play an important role in breaking down acetylcholine. Medications that slow these enzymes can sometimes help preserve the chemical messenger, improving symptoms in patients.

Scientists used computer simulations to study this process and predict how molecules behave inside the body.

"Our findings suggest that Beta sitosterol, one of the Aloe vera compounds, exhibits significant binding affinities and stability, making it a promising candidate for further drug development," said lead study author Meriem Khedraoui, a researcher at University of Casablanca in Morocco, in the press release.

Beta sitosterol attached to the key enzymes more strongly than any other compound tested in computer simulations. This suggests that the compound could be effective in slowing down these enzymes, the researchers noted.

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"These results highlight the potential of Beta sitosterol as a dual inhibitor, which could be crucial in managing Alzheimer's disease," added Khedraoui.

The team then examined the safety of such a compound to see if it could be used as a medication in the future. The compound was shown to be well-absorbed by the body and unlikely to be toxic at therapeutic levels.

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"The comprehensive analysis supports the potential of these compounds as safe and effective therapeutic agents," said Samir Chtita, another author of the study from the University of Casablanca, in the same press release.

The researchers acknowledged that the work is still in early stages, given that the results rely solely on computer simulations and not real-world examples.

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"Because aloe vera supplements are commonly sold over the counter, and because they have not been studied to validate their use in people with Alzheimer’s or other diseases that cause dementia or memory loss/cognitive decline, consumers need to be alert for any therapeutic claims made based on these results," Christopher Weber, Ph.D., senior director of global science initiatives at the Alzheimer’s Association, told Fox News Digital.

Inhibiting cholinesterase in the brain does not slow or stop the brain cell death and other damage caused by Alzheimer’s disease, noted Weber, who was not involved in the study.

ALZHEIMER’S DISEASE COULD BE REVERSED BY RESTORING BRAIN BALANCE, STUDY SUGGESTS

"So even if these findings are later shown to be successful in human studies, this would not be a ‘disease-modifying’ treatment," he added.

Further testing in lab experiments and clinical trials will be needed to confirm the efficacy of such a drug.

"There are many treatments in various stages of development — from laboratory work and animal models up to human clinical trials — that address the diseases in multiple ways," said Weber.

Those with concerns about cognitive symptoms should talk to a doctor, he advised. More information is also available at the Alzheimer’s Association website, www.alz.org.

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Common sleep aid could be quietly interfering with your rest, study suggests

Think your sound machine is helping you sleep? It might be doing the opposite.

A new study from the University of Pennsylvania Perelman School of Medicine found that listening to pink noise at bedtime could disturb REM sleep (dream sleep) and sleep recovery.

The research, published in the journal Sleep, found that earplugs were significantly more effective at blocking out traffic noise during sleep.

SIMPLE NIGHTLY HABIT LINKED TO HEALTHIER BLOOD PRESSURE, STUDY SUGGESTS

The researchers observed 25 healthy adults between the ages of 21 and 41, in an eight-hour, seven-night sleep lab simulation, according to a Penn Medicine press release.

The participants said they did not previously use noise to help them sleep, and did not have any sleep disorders.

During the experiment, the participants slept under different sound exposures, including aircraft noise, pink noise, aircraft noise with pink noise, and aircraft noise with earplugs. The participants completed tests and surveys each morning to gauge sleep quality, alertness and other health effects.

Exposure to aircraft noise was associated with about 23 fewer minutes spent in the deepest stage of sleep compared to no noise, the study found. 

Earplugs prevented this decline in deep sleep "to a large extent," the release stated.

EXPERTS REVEAL EXACT BEDTIME THAT COULD PREVENT LATE-NIGHT ‘SECOND WIND’ INSOMNIA

Pink noise at 50 decibels, which sounds similar to "moderate rainfall," was associated with almost a 19-minute decrease in REM sleep.

Aircraft noise and pink noise combined led to "significantly shorter" REM and deep sleep compared to noise-free nights. Time spent awake was also 15 minutes longer with this combination, which was not observed with solo aircraft or pink noise.

Participants said their sleep felt "lighter," the overall quality was worse, and they reported waking up more frequently when exposed to aircraft or pink noise compared to no noise, unless they used earplugs.

Lead study author Mathias Basner, M.D., Ph.D., professor of sleep and chronobiology in psychiatry, noted that REM sleep is important for "memory consolidation, emotional regulation and brain development."

FORCING AN EARLY WAKE-UP TIME COULD HARM YOUR HEALTH, SLEEP DOCTORS WARN

"Our findings suggest that playing pink noise and other types of broadband noise during sleep could be harmful — especially for children whose brains are still developing and who spend much more time in REM sleep than adults," he wrote in the release.

Basner noted it’s common for parents to place sound machines near their newborns or toddlers, with a "good intention" of helping them fall and stay asleep.

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There were some positive effects of pink noise, he said, including that it mitigated some deep sleep reduction and sleep fragmentation caused by "intermittent" environmental noise.

"If low amounts of deep sleep and sleep fragmentations are someone's main sleep issues, pink noise could be overall beneficial for them," he said. 

Individuals cycle through periods of deep sleep and REM sleep multiple times throughout the night, according to Penn Medicine. Deep sleep is important for physical restoration, memory consolidation and the clearing of toxins in the brain.

"Deep and REM sleep complement each other and collectively guarantee that we wake up restored in the morning, ready for the next day," the release stated.

Dr. William Lu, a San Francisco sleep expert and medical director of Dreem Health, said these findings are a "significant pivot" from the sound machine trend.

"While pink noise might mask external disruptions, it introduces a constant stimulus that the brain still has to process," he told Fox News Digital. "The most concerning finding is that we may be unknowingly sacrificing segments of our REM sleep."

Different types of noise could potentially have different impacts on sleep, Lu acknowledged.

White noise translates as "equal energy across all frequencies" and sounds like harsh radio static, the sleep expert said. Brown noise emphasizes lower frequencies, resulting in a "deep, bass-heavy rumble" like distant thunder or a heavy waterfall.

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While pink noise also has more energy at lower frequencies, but not as deep as brown, it creates a "perceptually balanced" sound like steady rainfall or wind.

"The study suggests that pink noise acts as a continuous auditory load that specifically fragments and reduces REM sleep," Lu summarized. 

Based on this type of research and data, the expert said he does not recommend using a sound machine as a "first-line" sleep aid in his own practice.

The researchers concluded that the impact of pink noise and other audio sleep aids needs to be studied more thoroughly.

"Overall, our results caution against the use of broadband noise, especially for newborns and toddlers, and indicate that we need more research in vulnerable populations on long-term use, on the different colors of broadband noise, and on safe broadband noise levels in relation to sleep," Basner said.

In an interview with Fox News Digital, the researcher noted that the study, funded by the FAA, does have limitations — including that it did not investigate the effect on sleep when pink noise is used for longer periods of time.

The study was also relatively small, Basner said, and the researchers haven’t yet examined differences between individuals.

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"Until we have more research, I would recommend that if somebody wants to use pink noise, they should do it at the lowest sound level that still works for them — and if falling asleep is the main problem, put the machine/app on a timer so that it shuts off after the subject falls asleep," he advised.

"Also, I would probably discourage general use [for] newborns and toddlers until we have more information."

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James Van Der Beek shared colorectal cancer warning sign months before his death

Prior to James Van Der Beek's death at age 48, the actor revealed the first warning sign of his colon cancer — and it’s one that did not seem alarming at the time.

The "Dawson’s Creek" actor's wife, Kimberly Van Der Beek, confirmed his passing in a social media post on Wednesday.

Following the announcement of his colorectal cancer diagnosis in November 2024, Van Der Beek told Healthline in August that "there wasn’t any red flag or something glaring."

COLORECTAL CANCER NOW DEADLIEST TYPE FOR CERTAIN GROUP OF AMERICANS, STUDY FINDS

"I was healthy. I was doing the cold plunge," he said. "I was in amazing cardiovascular shape, and I had stage 3 cancer, and I had no idea."

The one symptom that he did experience was a change in bowel movements, which the actor chalked up to an effect of his coffee consumption.

"Before my diagnosis, I didn’t know much about colorectal cancer," Van Der Beek said. "I didn’t even realize the screening age [had] dropped to 45; I thought it was still 50."

He ultimately underwent a colonoscopy, which revealed that the actor had stage 3 colon cancer.

COLORECTAL CANCER MAY CAUSE THESE 4 HIDDEN WARNING SIGNS, EXPERTS SAY

Professor Eitan Friedman, M.D., Ph.D., an oncologist and founder of The Suzanne Levy-Gertner Oncogenetics Unit at the Sheba Medical Center in Israel, confirmed that changes in bowel habits is the primary red flag that should raise the suspicion of colorectal cancer.

Others include fatigue (linked to anemia), blood in stool, weight loss, loss of appetite and abdominal discomfort, as Friedman, who has not treated Van Der Beek, previously told Fox News Digital.

Dr. Erica Barnell, M.D., Ph.D., a physician-scientist at Washington University School of Medicine — and co-founder and chief medical officer at Geneoscopy — noted that Van Der Beek’s experience of having no "glaring" signs is common.

"Many colorectal cancers develop silently, without obvious symptoms," Barnell, who also did not treat the actor, previously told Fox News Digital. "By the time symptoms appear, the disease may already be advanced."

Symptoms are "especially worrisome" for those 45 and older who have at least one first-degree relative with colon cancer or other GI malignancies, and those with active inflammatory bowel disease, such as ulcerative colitis or Crohn’s disease, added Friedman, who is also an advisory board member at SpotitEarly, a startup that offers an at-home breath test to detect early-stage cancer signals.

The overall chance of an average-risk person getting colorectal cancer over a lifetime is 4% to 5%, according to Friedman.

"Colonoscopy at age 45 onwards, at five- to 10-year intervals, has been shown to lead to early detection of polyps that have the potential to become malignant, and to allow for their removal as an effective means of minimizing the risk of malignant transformation," he said. 

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Unfortunately, Barnell noted, "screening compliance in the U.S. remains below national targets, and gaps are widest in rural, low-income and minority communities."

To help close those gaps, she called for greater access to "accurate, noninvasive screening technologies," along with efforts to increase public awareness.

"Most people don’t like talking about bowel habits, but paying attention to changes can save your life," Barnell said. "Screening gives us the chance to find problems early — often before you feel sick — and that can make all the difference."

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Fox News Digital previously reached out to Van Der Beek’s representative for comment.

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