What your butt shape could reveal about your health, according to scientists

An often-overlooked part of the body may reveal important clues about overall health.

Researchers from the University of Westminster in the U.K. discovered that the shape of the gluteus maximus muscle in the buttocks changes with age, gender, lifestyle and frailty, as well as certain conditions like osteoporosis and type 2 diabetes.

Using advanced MRI scans that create 3D images, researchers revealed "distinct" patterns in the gluteus maximus associated with type 2 diabetes.

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This suggested that the shape of the muscle, rather than the size, may "reflect underlying metabolic differences," a press release stated.

The findings were presented in December at the annual meeting of the Radiological Society of North America (RSNA) in Chicago.

Unlike previous studies looking at muscle size or fat, the 3D imaging identified exactly where the muscle changes occur, according to the researchers.

As one of the largest muscles in the human body, the gluteus maximus "plays a key role" in metabolic health, according to lead study author E. Louise Thomas, Ph.D., professor of metabolic imaging at the University of Westminster’s School of Life Sciences.

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The researchers analyzed more than 61,000 MRI scans from a large UK health database to better understand the muscle’s structure.

The data also included the participants’ physical measurements, demographics, disease biomarkers, medical history and lifestyle habits. The researchers studied how these variables were linked to muscle shape over time.

"People with higher fitness, as measured by vigorous physical activity and hand grip strength, had a greater gluteus maximus shape, while aging, frailty and long sitting times were linked to muscle thinning," study co-author Marjola Thanaj, Ph.D., a senior research fellow at the University of Westminster’s Research Centre for Optimal Health, said in the release.

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The researchers concluded that butt shape changes may indicate an "early functional decline" and "metabolic compromise" in type 2 diabetes patients.

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Men with type 2 diabetes showed muscle shrinkage, while women displayed enlarged muscle, likely due to "infiltration of fat" within the muscles, according to the researchers.

These results suggest that men and women have "very different biological responses to the same disease," Thanaj suggested.

Men who were categorized as "frail" were recognized as having more "general shrinkage" across the gluteus maximus, but women experienced a "limited" frailty effect.

Strengthening the glutes is an "investment in long-term health," according to Tanya Becker, co-founder of Physique 57 in New York City.

"While full-body strength training is essential, focusing on your glutes — the largest muscle group in your body — deserves special attention," she told Fox News Digital.

Becker refers to the glutes as the body’s "shock absorbers," because they protect the lower back, knees and hips from taking on stress they weren’t designed to handle. 

Larger muscle groups also burn more calories and help regulate blood sugar, the expert added, noting that muscles are often referred to as the "organ of longevity."

Strengthening the glutes also helps to protect the lower back, hips and knees, and also improves posture and balance, reducing the risk of falls and improving mobility.

Becker recommends traditional weighted exercises like squats, lunges and bridges, although they are not suited for everyone, especially older adults with injuries and joint pain.

"Pilates and barre classes offer bodyweight exercises that are ideal for beginners or individuals with physical limitations," she suggested. "They can be done anytime, anywhere, making them accessible for beginners before progressing to weighted versions."

Becker shared the following three glute exercises that improve hip mobility, stability and overall strength.

Start on the hands and knees, engage your core, and lift one leg off the floor (bent or straight). Pulse up and down a few inches for 30 to 60 seconds, then repeat on the other leg.

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Lie on your side with knees bent at 90 degrees in front of you. Lift your top knee away from your bottom knee, then lower slowly. 

For an increased challenge, lift both feet off the ground while keeping the heels together. Repeat for 30 to 60 seconds per side.

Lie on your back with knees bent and feet parallel, a few inches from your hips. Engage your abs and squeeze your glutes to lift your hips toward knee height, then lower. 

If you feel pressure in your neck, you’ve lifted too high. Perform for 30 to 60 seconds. Complete three sets with 30-second rests between.

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Those looking to start a new fitness routine should first consult with a doctor.

Fox News Digital reached out to the study authors for comment.

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First-of-its-kind fentanyl vaccine targets overdoses before they start

A vaccine to protect against fentanyl’s deadly effects is headed for clinical trials in humans.

The vaccine, which showed positive results in studies of mice and rats, is designed to block fentanyl from entering the brain, blocking its effects and preventing overdoses.

If approved, it would become the first treatment to prevent overdoses of fentanyl, which is the leading cause of drug overdose death, statistics show. This is different than treatments like naloxone, which reverse the effects after an overdose.

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The vaccine is designed to create antibodies against fentanyl, which keeps the drug from crossing the blood–brain barrier. It contains a synthetic fragment of fentanyl attached to a protein called CRM197, along with dmLT, an immune-activating compound. 

This combination stimulates the immune system to produce antibodies that capture fentanyl in the bloodstream before it can reach the brain, according to the University of Houston's Colin Haile, co-founder and scientific adviser of ARMR Sciences, which licensed the vaccine.

"In a vaccinated individual, those anti-fentanyl antibodies are in the blood," Haile told Fox News Digital. "So if they consume fentanyl, the antibodies grab onto the drug and prevent it from getting into the brain. They would feel no effects if they ingest fentanyl — absolutely none. And they would not overdose."

Eventually, he said, the fentanyl would be eliminated from the body.

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In the mice and rat studies, the animals still had antibodies against fentanyl six months after vaccination, added Haile, who is also a research associate professor of psychology at UH and a founding member of the UH Drug Discovery Institute.

While some have questioned whether such a vaccine would indirectly encourage drug use, Haile pointed out that for vaccinated people, the drug would have "no euphoric effects," so those seeking a "high" would not get it.

The main benefit, according to Haile, is that the vaccine would reduce the potential health dangers of fentanyl.

"Respiratory depression is the primary effect that induces death from this highly potent synthetic opioid," he said.

Following successful testing in mice and rats, the first human clinical trial is slated to begin in early 2026 at the Center for Human Drug Research, which is associated with the University of Leiden in the Netherlands.

The small phase 1 trial will enroll about 40 participants, focusing on safety and immune response.

After the phase 1 trial for safety, a phase 2 trial will test whether the vaccine effectively blocks fentanyl’s effects in humans.

The primary limitation is that data is so far only available for mouse models, and it’s unknown how effective the vaccine would be in humans.

Haile told Fox News Digital that there were no adverse side effects reported in the animal study, likely because the ingredients of the vaccine are proteins that have already been used in other combinations in humans, so their safety profile is already known.

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"Also, unlike other vaccines, we use extremely low doses of the components," he noted. "We have put the vaccine into a lot of animals and have not seen any adverse side effects at all."

Even in a toxicology study, during which the researchers administered 20 times the dose of the vaccine that would be given to humans, they still saw no overt signs of toxicity, according to Haile.

Haile mentioned several different use cases for the vaccine, primarily those with opioid use disorder who want to quit using fentanyl. It could also be used by first responders and healthcare workers who want to reduce the risk of accidental exposure.

Military and national security personnel could also benefit from the vaccine, Haile said, as it could help protect against fentanyl and fentanyl-like compounds that have been used as chemical threats.

Finally, parents may be seeking protection for at-risk teens or young adults, as fentanyl has been known to be mixed with other substances, such as marijuana.

Looking ahead, Haile said this could pave the way for the approval of other anti-drug vaccines, such as cocaine and methamphetamine, which are already in the works.

"If we can tackle the primary ones — fentanyl, cocaine and methamphetamine — we will be saving hundreds of thousands of lives," he added.

Dr. Marc Siegel, senior medical analyst for Fox News, said the progress of the vaccine is a "very exciting advance with a huge upside."

"I am very glad it is now entering human trials — it is being very well-studied," he told Fox News Digital. "This is likely to prevent many overdoses where a patient is sedated and stops breathing as a result of fentanyl."

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The antidote for fentanyl (Narcan) is limited because fentanyl lasts for many hours, but the Narcan (an opioid antagonist) wears off after only a few hours and has to be readministered, Siegel pointed out.

"You want to make sure this vaccine is limited to those really at risk for opioid overdoses and addiction, because fentanyl is also a useful pain medication for cancer and a useful agent for anesthesia," the doctor added.

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The vaccine was developed with funding from the U.S. Department of Defense and licensed to biotech startup ARMR Sciences.

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Rockstar fitness routine: Could you survive Mick Jagger’s brutal workout?

Mick Jagger still sprints, dances and sings across the stage during Rolling Stones concerts, which can stretch close to two hours. That may not seem unusual for the frontman of a wildly popular rock band — except that Jagger is now 82 years old.

In interviews over the years, the octogenarian has credited his onstage endurance to a combination of constant training and good genetics.

Jagger has said his regimen includes two dance rehearsals a week, "a few" gym sessions, meditation and yoga, according to recent reports. 

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The singer's workouts reportedly involve everything from swimming and kickboxing to cycling and ballet. He has described the routine as "training for stamina," not just to "go crazy."

The diversity of Jagger's routine is a key reason it works, according to fitness experts.

"I’m a huge advocate of diversifying your workouts," said Marc Santa Maria, vice president of group fitness at Crunch Fitness in New York. "Our bodies are meant to move in multi-directional ways and varying speeds, ranges of motion, positions and intensities."

"Sticking with the same workout in the same category each week won’t hit the different ways our bodies need to be maintained and challenged," he added.

Even workouts that offer multiple benefits, such as yoga, can lead to plateaus over time as the body adapts, the expert noted.

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Alissa Mosca, fitness trainer and regional operations manager at Planet Fitness in New York, told Fox News Digital that one of the biggest advantages of incorporating different training methods is that it creates "muscle confusion." 

"Varying movements, intensities and rhythms force the body to adapt, helping to activate all muscle groups more effectively," she said. "It’s a bit of a ‘use it or lose it’ philosophy — if we don’t actively support flexibility and mobility, we risk losing them."

Santa Maria said Jagger’s mix of high-intensity cardio, strength training, dance, yoga and meditation is a well-rounded approach for endurance, muscle maintenance and mental health, while also keeping workouts engaging.

"Mick Jagger’s workout plan is extensive, highly individualized and something he gradually worked up to over time," Mosca noted. "His body responds well because it’s been conditioned for that level of intensity."

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While this workout is "achievable for anyone," the expert cautions that jumping straight in likely wouldn't be sustainable. Instead, it's important to ease into it. 

"Think of this type of routine like a puzzle," Mosca advised. "You need to find the pieces that work best for you."

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Santa Maria agreed that Jagger’s approach may be more realistic than many assume. "I’m an average, everyday person who simply wants to move well, enjoy daily life and stay active for the people and activities I love," she said. "If I can do it, so can anyone."

But for those who don’t feel capable of matching Jagger’s intensity, Santa Maria recommends focusing on what feels manageable. "Trust your instincts — you know what your body and mental health need," he said.

Clinical guidelines from Mayo Clinic recommend at least 150 minutes of moderate aerobic activity per week for adults, along with muscle-strengthening activities at least twice weekly. Sports medicine studies suggest that people with long-term conditioning can safely exceed those minimums when training is progressive and closely managed.

Workouts should be built around individual ability and preference, according to Santa Maria. 

Some people respond better to shorter, more frequent sessions, he said, adding that even beginners can benefit from about 20 minutes of varied movement most days, particularly if they spend long periods sitting.

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For those interested in adopting a similar approach, the expert recommends starting with structure. Deciding ahead of time which days are dedicated to which types of movement — and removing hesitation by laying out clothes, preparing equipment or booking classes in advance — can improve consistency, he advised.

Beyond physical benefits, Santa Maria said adding variety to workouts helps to prevent boredom, which can improve adherence over time.

"The main risk is that it can feel overwhelming for someone who’s completely new to working out," he said, noting that too many options can lead to decision fatigue.

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According to Cleveland Clinic physicians, dramatic changes in exercise intensity or volume can increase injury risk, especially among older adults, while gradual training over decades allows the body to adapt to higher demands. 

It’s important to consult a professional before making any drastic changes to your lifestyle.

Fox News Digital reached out to Mick Jagger’s team for comment.

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Catholic influencer's 5-year-old son dies after 11-day flu battle followed by thousands

A Catholic influencer announced Thursday that his 5-year-old son had died after an 11-day battle with a severe case of the flu, a loss that unfolded publicly as he shared updates almost daily online.

Paul J. Kim, who shares faith-based content with more than 300,000 followers on Instagram, said his son Micah died on New Year’s Eve. 

In an emotional video posted Thursday, Kim thanked supporters for their prayers and asked for privacy as his family grieves.

"We are so proud of him," Kim said in the video. "I want to thank you from the bottom of my heart, as his dad, on behalf of my family, for all the ways you guys prayed and lifted us up during this time. It’s been the hardest thing I’ve ever been through in my life, and it continues to be."

Kim first shared news of Micah’s illness Dec. 21, when he posted that his son was being taken to a hospital by ambulance after a medical emergency. 

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In subsequent updates, Kim said doctors described Micah’s illness as an unusually severe case of the flu. Kim later told followers that Micah had been placed on life support and urged people to pray. 

In later updates, he revealed that the flu infection had turned septic and triggered seizures. At the time, Kim said doctors described the case as rare and serious.

In a Dec. 30 update, Kim said his son’s condition had worsened and that Micah was in a coma as doctors and family members worked to give him as much time as possible.

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Kim’s posts, some of which showed Micah in the hospital, were viewed millions of times. 

Throughout the ordeal, Kim referred to his son as a fighter and "my hero."

In a written Instagram post, he quoted Job 1:21, "The Lord gave, and the Lord has taken away; blessed be the name of the Lord" and said Micah had entered "the never-ending glory, love, and peace of God." 

He added that while his family’s hearts are broken, they continue to rely on their faith.

Kim also asked followers to pray for his family as they learn "how to live by faith and not by sight." 

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According to recent data, the CDC reported 288 pediatric deaths in the 2024-25 season.

This has been a record high for a non-pandemic year, mostly among unvaccinated kids, with 70% having underlying conditions like asthma. 

In addition, a new so-called "super flu" strain has emerged this season, a mutation of influenza A H3N2 called subclade K. It's highly contagious and aggressive and is sweeping the nation this season.

On average, around 20,000 children under 5 are said to be hospitalized annually, with younger children (under 6 months) facing the highest mortality risk, highlighting the importance of annual vaccination, according to the CDC.

Kim did not immediately respond to Fox News Digital’s request for comment.

Fox News Digital's Angelica Stabile contributed to this report.

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6 pillars of a healthier lifestyle in 2026, from experts on staying young

About 30% of Americans make at least one New Year’s resolution, statistics show, generally focused on exercising, eating healthier and losing weight.

However, less than 10% of people stick with their resolutions throughout the year, with nearly a quarter quitting in the first week.

To boost the success rate of resolutions, two doctors recommend pivoting from "quick fixes" and focusing more on science-based ways to achieve long-term wellness.

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Dr. Shai Efrati, a leading expert in brain health and longevity, and Dr. Joseph Maroon, an 84-year-old NFL neurosurgeon and superager, shared the following six tips with Fox News Digital.

Retirement can potentially accelerate physical and cognitive decline, Efrati warned, especially if it means withdrawing from meaningful activity. 

"Research consistently shows that continued engagement in work — whether full-time, part-time or even purpose-driven projects — is associated with better cognitive resilience, cardiovascular health and overall longevity," the doctor, who is founder and director of the Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center in Tel Aviv, Israel, told Fox News Digital.

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Continuing to seek out mental and social challenges stimulates brain metabolism, neuroplasticity and vascular health, according to Efrati, who also serves as chair of the medical advisory board at Aviv Clinics, which operates in Florida and Tel Aviv.

"In other words, staying professionally active keeps the brain ‘in training,’ much like exercise does for muscles," he said. "The key isn’t working longer out of obligation; it’s staying engaged in something that challenges and fulfills you."

Maroon, professor of neurological surgery at the University of Pittsburgh Medical Center, emphasizes the importance of managing stress for optimal wellness.

"The key is to balance priorities — work, family and friends, spirituality and regular exercise — to reduce chronic stress, which I’ve seen contribute to poor sleep, anxiety and cardiovascular issues," he shared.

"In my experience, this ‘stress balance’ is a key to health and longevity and may also help lower the risk of neurodegenerative diseases like Alzheimer’s."

"A strong sense of purpose is one of the most powerful, and underestimated, predictors of longevity," Efrati said.

Studies show that people who have meaningful pursuits have lower levels of chronic inflammation and a reduced risk of early death, the doctor noted.

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"Purpose activates both psychological and biological pathways. It influences stress regulation, immune balance and even cellular repair mechanisms," the expert said. 

"Whether purpose comes from work, family, creativity, service or learning, it acts as a biological stabilizer, giving the body a reason to invest in long-term maintenance and repair."

Research suggests that "regular spiritual or communal practice" is linked to a reduced risk of early death, according to Maroon, who is also author of "Square One: A Simple Guide To A Balanced Life."

"I believe it can be an important contributor to overall well-being," he said, adding it’s also been linked to lower rates of depression. 

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"Whether through faith, service or a consistent community routine, these practices can provide connection, perspective and resilience at a time of year that can be emotionally challenging for many," the doctor said.

Efrati says food should be viewed not merely as calories, but as fuel for cellular energy production and repair.

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"Diets rich in whole, unprocessed foods, particularly the Mediterranean diet, provide the nutrients that support mitochondrial function, vascular health and brain metabolism," he said.

The doctor recommends incorporating leafy greens, berries, legumes, nuts, olive oil, and fatty fish like salmon, which deliver antioxidants, polyphenols, omega-3 fatty acids and essential micronutrients that reduce inflammation and support longevity at the cellular level.

"The goal isn’t restriction, it’s nourishment — supplying the body with what it needs to repair, adapt and thrive over time," Efrait added.

Maroon, who is also the medical consultant of the Pittsburgh Steelers, considers quality sleep a "cornerstone of brain health and longevity." 

"When you sleep well, you support healthy metabolism and immune function, and you also improve mood, focus and stress resilience," he said.

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"Just as important, good sleep makes it easier to maintain the daily habits that protect long-term health, including better nutrition, regular exercise and more consistent decision-making."

Adults should get between seven and nine hours of sleep nightly to support brain, immune and cardiovascular health, according to medical experts.

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Oprah joins wave of celebrities who revealed dramatic weight loss in 2025

Celebrities have been striving for health in 2025, with many dropping significant amounts of weight — in many cases with the help of GLP-1 medications like Ozempic.

Below are four A-list stars who shared their weight-loss journeys this year, with or without the help of prescription drugs.

Long-time talk show host Oprah Winfrey was recently featured in an exclusive interview with People Magazine, during which she discussed her weight loss and her new book, "Enough: Your Health, Your Weight and What It’s Like to Be Free."

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Winfrey, 71, began taking a GLP-1 medication in 2023 but attempted to quit just six months in to see if she could lose weight without it. Regardless of her diet and exercise routines, the media mogul said she still gained back 20 pounds after stopping the drug.

"It's going to be a lifetime thing," she shared. "I'm on high blood pressure medication, and if I go off the high blood pressure medication, my blood pressure is going to go up. The same thing is true now, I realize, with these medications. I’ve proven to myself [that] I need it."

Winfrey revealed that her default weight, at 211 pounds, was not healthy, as she was pre-diabetic and had high cholesterol.

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The author told People that she injects a GLP-1 weekly, and has also paid out of pocket for friends who could not afford the drug.

Winfrey added that the absence of food noise "has given me a quiet strength that comes with everything I do. Everything is just calmer and stronger."

Regardless of GLP-1 access or tolerance, Winfrey encouraged those struggling with obesity that it is "not your fault."

"I want people to stop blaming [themselves] for genes and an environment [they] can’t control," she said. "I want people to have the information, whatever you choose to do with it, whether you get the medications, or whether you want to keep dieting."

Comedian Amy Schumer dropped 50 pounds after being diagnosed with Cushing’s syndrome, a hormonal disorder that can cause extreme swelling, fatigue and potentially fatal complications.

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Schumer's transformation sparked conversation online, to which she responded in a now-deleted Instagram post that shut down speculation about cosmetic enhancements.

"I didn’t lose 30 lbs — I lost 50," she emphasized on social media, adding that she does not get Botox or filler.

Schumer doubled down that her weight loss was not about her appearance, but about staying alive. She also confirmed that she has used the GLP-1 medication Mounjaro.

"Not to look hot, which does feel fun and temporary," she said. "I did it to survive. I had a disease that makes your face extremely puffy that can kill you, but the internet caught it and that disease has cleared."

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"Sorry for whatever feeling it’s giving you that I lost that weight," she added. "I’ve had plastic surgery over the years and I use [Mounjaro] … I’m pain-free. I can [play] tag with my son."

The actress also addressed her shifting hormones, saying that she’s "happy to share more if anyone has any questions about how I’m looking or feeling or where I am in my perimenopause process."

"All About That Bass" singer Meghan Trainor has also confronted haters for "body-shaming" her after a dramatic 60-pound weight loss.

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Trainor recently told "Entertainment Tonight" that she’s "never felt better" and is taking care of her health for the first time since having her two children.

"I feel great, and that’s when people attack me," she said, noting that the criticism is only getting "louder" and "meaner." Despite the online noise, Trainor emphasized that she’s focused on her well-being.

"I’m taking care of myself," she reiterated. "I have to find a way to not be affected by that."

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The singer's health journey began by eliminating gluten and dairy from her diet after finding out that she had a "leaky gut." The artist also got serious about strength training.

Trainor’s own fitness trainer, Bella Maher of Malibu Bodies, posted before-and-after photos of the pop star on Instagram, revealing how hard she worked before introducing a GLP-1 drug.

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"Watching her transform from the inside out has been one of the most meaningful parts of my work," the caption reads. "She did so much of this on her own before ever introducing a GLP-1, and even after starting it, the medication was simply a support, not the reason for her results. GLP-1s can be a powerful tool, but they’re certainly not a transformation plan. SHE is the reason this worked."

Singer and musician Lizzo stepped out this year with a slimmer figure, as the public speculated about her GLP-1 use.

During a discussion about Ozempic on Trisha Paytas’ "Just Trish" podcast in June, the musician shared that she had "tried everything" for weight loss.

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"Ozempic works because you eat less food," she said. "It makes you feel full. So, if you can just do that on your own and get mind over matter, it's the same."

Lizzo shared that ending her vegan diet and eating more meat helped her stick to a caloric deficit, since she once consumed "a lot of fake meat," bread and rice.

"And I had to eat a lot of it to stay full … I was consuming 3,000 to 5,000 calories a day."

"For me, when I started eating whole foods, like beef and chicken and fish, I was actually full and not expanding my stomach by putting a lot of … fake things in there that weren't actually filling me up," she added.

The Grammy winner revealed that her biggest inspiration for losing weight was to alleviate the intense back pain she would feel after performing on stage.

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"My body was hurting," she said. "I want to be Tina Turner. I want to be doing stadium shows when I’m 70. If my back is on this track right now, there’s no way."

Fox News Digital’s Stephanie Giang-Paunon contributed to this report.

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