Health stories of the week you might've missed: Catch up quickly here

Fox News Digital publishes an array of health pieces all week long to keep you in the know on wellness topics, cancer risk factors, innovative surgeries, nutrition tips, mental health trends and much more — plus, personal stories of people and families overcoming great obstacles.

As your Sunday winds down and you look ahead to the coming week, check out some of the top recent stories in Health that you may have missed, or have been meaning to check out. 

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These are just a few of what's new, of course. 

There are many more to see at http://www.foxnews/health. 

Two months after having abdominal surgery, the Princess of Wales released a video on Friday announcing her cancer diagnosis. Doctors are now speculating about exactly what type of cancer she may have — which she has not yet disclosed. Click here to get the story. 

Half a dozen high-school students in the U.S. were finalists in this year’s Regeneron Science Talent Search for their progress toward improving the diagnostics and treatment of cancer. The teens shared their motivations, goals and hopes with Fox News Digital. Click here to get the story.

Elon Musk uses ketamine to boost his mental health, the billionaire said in a video interview. When asked about drug use, Musk — CEO of Tesla and SpaceX — answered, "There are times when I have sort of … a negative chemical state in my brain, like depression, I guess." Musk also shared how ketamine helps him. Click here to get the story.

A Massachusetts man, 62, was suffering from end-stage kidney disease when he received a successful pig kidney transplant at Mass General Hospital. Experts hope the successful surgery could open a "new frontier" in organ transplantation. Click here to get the story.

The COVID pandemic led to many thousands of missed prostate cancer diagnoses in the U.K., a recent study found. Doctors weighed in on what needs to happen to ensure the affected men receive the care they need. Click here to get the story.

Certain medications cause side effects that may impair your ability to operate a vehicle, according to the FDA. If you’re taking these drugs, it’s best to consult a doctor before getting behind the wheel. Click here to get the story.

It may be tempting to skip the nighttime task, but two dermatologists discuss the reasons why going to bed with a clean face is so important. Click here to get the story.

After facing her own personal caregiver struggles, a former NASA scientist created an artificial intelligence-powered app that predicts when seniors may need long-term care — and how much it will cost. Find out how the app is helping families get the information they need sooner rather than later. Click here to get the story.

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Cancer and Princess Kate: What type of diagnosis did Kate Middleton receive?

Kate Middleton’s Friday video announcement of her cancer diagnosis may have shed some light on why she’s been out of the public eye lately — and there has been an outpouring of support for her and the royal family ever since — but it left another looming question in its wake.

What kind of cancer does the Princess of Wales have?

While experts agree that Middleton is entitled to medical privacy and is under no obligation to reveal the details of her condition — and that few people know her specific medical details — some doctors have shared ideas and theories about the potential origins of the disease based on their own expertise.

KATE MIDDLETON ANNOUNCES SHE HAS CANCER, UNDERGOING CHEMOTHERAPY TREATMENT

Dr. Marc Siegel, clinical professor of medicine at NYU Langone Medical Center and a Fox News medical contributor, said he's spoken with multiple cancer doctors about the possible origins of the princess’ cancer diagnosis based on earlier available information. 

"One of the heads of medical oncology at NYU Langone Cancer Institute believes it may be colon cancer, and that the major abdominal surgery she had may have been a bowel resection for Crohn’s disease," Siegel told Fox News Digital. (Neither Siegel nor the doctors he spoke with have personally evaluated Middleton.)

It has been reported in previous years that Middleton has Crohn’s disease, which is a chronic inflammatory bowel disease affecting the lining of the digestive tract.

"Inflammatory bowel disease greatly increases the risk for colon or bowel cancer," Siegel added.

PRINCESS KATE MIDDLETON UNDERGOING ‘PREVENTATIVE CHEMOTHERAPY’ AFTER CANCER DIAGNOSIS: ‘STRONGER EVERY DAY’

It's been widely reported that Middleton had major abdominal surgery in January.

A large share of Crohn’s patients — up to half — will need surgery at some point to alleviate symptoms, according to the Crohn’s and Colitis Foundation.

"She could have been having bowel surgery for the Crohn’s and they later found it on pathology," Siegel hypothesized, once again stressing a professional guess based on years of experience. 

That kind of surgery would also explain the more extensive recovery time, he added.

Chemotherapy for colon or bowel cancer would include Oxiplatin (intravenous) and Xeloda (oral) for several weeks, according to Siegel.

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It is also possible that gynecological cancer could have been detected, experts say.

"[The surgery] could have been a hysterectomy, and she may have been found to have ovarian, uterine or cancer of the cervix, which was local and removed," Siegel surmised. 

"But going against this [idea] is that there is no sign of hair loss, which is caused by Taxol, the predominant intravenous treatment for these gynecological cancers."

Ovarian cysts may be seen on routine imaging and can be removed laparoscopically — and the diagnosis of cancer is often found later, the doctor said.

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The chemo that is administered for early-stage colon cancer doesn't routinely cause hair loss, Siegel noted.

"I have now spoken to several experts — both top oncologists and colorectal surgeons — and they all say the same thing," he added. 

"She likely has either early colon or bowel cancer that was removed and cured surgically, or ovarian or uterine cancer."

Whatever type of cancer the princess has or had — Siegel said he has hope that her prognosis could be good.

"I have diagnosed a lot of cancer [cases], unfortunately, but more and more, it's early enough to be cured," he said.

"Whatever type of cancer it is, they appear to have gotten it out."

In her video message, Middleton said she has begun a treatment regimen of "preventative chemotherapy."

"The good news is that the word ‘preventative’ was used, which would mean that the cancer was removed in its entirety, presumably by bowel resection, and that the chemo is being given to increase the chances of no recurrence," Siegel said.

The chances of a recurrence are much lower with chemotherapy, the doctor added.

Above all, Siegel emphasized Middleton’s right to privacy.

"We need to respect her privacy and show compassion and empathy, especially given her young age and young children," he told Fox News Digital.

"These records should be sacrosanct," he also said about her personal medical details. 

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On Friday in her video message, Middleton revealed that after her abdominal surgery, doctors initially believed her "condition was non-cancerous," but further testing proved otherwise.

"My medical team therefore advised that I should undergo a course of preventative chemotherapy and I am now in the early stages of that treatment," she shared.

Angelica Stabile and Caroline Thayer, both of Fox News Digital, contributed reporting. 

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Sleep disorders and suicide: A mental health expert reveals the concerning link

This story discusses suicide. If you or someone you know is having thoughts of suicide, please contact the Suicide & Crisis Lifeline at 988 or 1-800-273-TALK (8255).

We’ve all experienced the irritability that comes with a lack of shuteye — but an extended period of poor sleep health could lead to far more serious effects than that.

Some experts warn that people who have chronic sleep struggles are more likely to experience suicidal ideations.

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Fox News Digital spoke with Taft Parsons III, M.D., vice president and chief psychiatric officer at CVS Health in Birmingham, Michigan, about this concerning link.

Research shows that 42% of Americans have shared concerns about their mental health, and 18% say they were plagued with suicidal thoughts at some point during this past year, according to Parsons.

Suicide is very complex with several intersecting risk factors, he noted. 

"There is no single cause of suicide — it is a convergence of health factors, along with other psychosocial and environmental variables that can increase the chances someone may take their own life," he told Fox News Digital. 

These can include social and environmental factors, such as prolonged stress and legal and financial issues, he noted.

SUICIDE RATES REACH ALL-TIME HIGH IN US, PER CDC DATA

Past trauma and psychological health issues — like depression, substance use disorder and sleep — can also be factors. 

"Some of these factors can be more challenging than others to address, but seeking help for sleep issues or disorders can be a step toward addressing one potential risk factor," said Parsons.

Inadequate sleep can negatively impact critical functions like decision-making, impulse control, problem-solving abilities, emotion regulation and resilience, Parsons noted. 

"When a person is struggling with sleep deprivation, it can increase various adverse health outcomes, including heart disease and type 2 diabetes," he said.

"It can also lead to increased depression and anxiety, both of which can play a significant role in suicide."

Well-rested people are better equipped to face life's challenges, effectively manage stress and maintain a positive mindset, according to the expert. 

"Improved sleep can also reduce impulsivity and emotional dysregulation, both of which can be associated with suicidality," he said.

People who have suicidal ideations will often exhibit sudden changes in behavior, said Parsons. 

Those can include new sleep issues such as insomnia or sleeping too much. 

IMPROVE YOUR SLEEP BY OPTIMIZING 6 BIOMARKERS: ‘INTEGRAL TO HEALTH’

"Similarly, we view withdrawal from friends and family, reckless actions or increased use of substances as warning signs," he told Fox News Digital. 

"So, focusing on the sudden or uncharacteristic change in sleep is the critical factor, not necessarily the number of nights."

Recognizing common signs of sleep deficiency is crucial to stopping it from interfering with a person’s mental health, according to Parsons.

When people are sleep-deprived, they will often experience problems with concentration, memory, decision-making, problem-solving, and regulation of emotions and behavior, he pointed out.  

"Individuals who are not well-rested, and may also have difficulty regulating their emotions, are at increased risk of poor decision-making and have a negative ability to cope effectively when faced with overwhelming stresses," Parsons warned.  

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"If these problems come on suddenly, escalate or become recurring, they may indicate more serious or underlying issues and indicate a mental health issue."

Experts recommend that adults get between seven and nine hours of sleep per night.

Children and teens generally need more sleep than adults. 

For those struggling with sleep challenges, experts recommend seeking treatment when they’re not able to manage the issue themselves.

"Many people unwittingly have habits that are detrimental to a good night’s sleep, and thus should start with a sleep hygiene program for several weeks," Parsons suggested.

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"If you notice someone is displaying warning signs of suicide, including sudden sleep issues, or other signs including mood changes or verbal cues, it is important to reach out, have an honest conversation, express concern, and help connect them to support," he said.

Even if suicide turns out to not be a concern, the person may still feel comforted, supported and relieved by someone taking the time to connect and listen, Parsons noted.

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It’s not necessary for people to wait until they’re in crisis to reach out for support, he emphasized. 

"There are resources available to help prioritize well-being, no matter where on the spectrum of mental health someone may fall," he said. 

"The earlier someone connects to support and resources, the sooner they can feel better and increase their overall resilience."

If someone is exhibiting signs of suicide ideation, it is crucial the person gets help immediately by calling or texting 988 to reach the 988 Suicide and Crisis Lifeline.

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Newly approved cancer drug targets aggressive form of ‘deadly disease’

A new drug regimen for certain types of pancreatic cancer recently received approval from the U.S. Food and Drug Administration (FDA) — the first new medication in nearly a decade.

Onivyde (irinotecan liposome), an injectable medication made by Ipsen, has been approved for use along with oxaliplatin, fluorouracil and leucovorin as a regimen for patients with metastatic pancreatic adenocarcinoma (mPDAC).

This type of cancer is an aggressive malignancy with an average life expectancy of between eight and 11 months, according to the National Institutes of Health (NIH).

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The approval was based on a randomized, controlled trial that included 770 patients with metastatic pancreatic adenocarcinoma who had not previously received chemotherapy, according to an FDA press release.

The group of patients who received the new regimen via IV infusion showed "significant improvements" in survival rates and response rates compared to the control group.

The drug regimen is administered via IV for 90-minute sessions every two weeks.

"I am hopeful that this regimen represents a new reference — meaning we will add to this in the future," Dr. Zev Wainberg, professor of medicine and co-director of the UCLA GI Oncology Program in Los Angeles, told Fox News Digital.

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"We needed clarity on the data before proceeding, which the Phase 3 trial provides."

Metastatic pancreatic cancer is one of the most difficult cancers to treat, Wainberg noted, as it doesn’t respond as well to new drugs that work in other types of the disease. 

"Patients are unfortunately often quite sick, and many cancers move too fast for a drug to work as they might in other cancers," he noted.

Dr. Marc Siegel, clinical professor of medicine at NYU Langone Medical Center and a Fox News medical contributor, said the drug is "a useful new tool, but not a game-changer."

"It works well in conjunction with other chemotherapies that have been used for widespread pancreatic cancer," Siegel told Fox News Digital. 

"It works by interfering with DNA replication in the cancer and by damaging the tumor’s DNA repair."

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Dr. Peter Hosein, M.D., associate director of clinical research at the University of Miami’s Sylvester Comprehensive Cancer Center’s Pancreatic Cancer Research Institute, also commented on the new approval.

"Pancreatic cancer is a deadly disease where meaningful progress is sorely needed in prevention, early detection and treatment to improve outcomes," he told Fox News Digital.

Onivyde is a new formulation of an old drug that is "almost identical," Hosein said.

"So, although this is a new approval, it does not really represent meaningful progress," he told Fox News Digital. 

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Onivyde is also "substantially more expensive" than Irinotecan, the existing standard medication, Hosein pointed out. 

"There are many doctors and scientists working around the clock on this disease and the survival rates are slowly improving," he said. 

"We need to continue focusing on breakthrough therapies that will truly move the needle to help our patients." 

The most commonly reported side effects of Onivyde are diarrhea, nausea, vomiting, fatigue, decreased appetite, abdominal pain, mucosal inflammation, constipation and weight loss, the FDA stated. 

"All drugs have a safety profile that needs to be taken seriously," Wainberg said. 

"Here, most of the combination produced GI upset — diarrhea and sometimes dehydration — so prophylactic (preventative) management is critical."

Fox News Digital reached out to Ipsen, a French biopharmaceutical company headquartered in Paris, France, for additional comment.

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Princess Kate Middleton undergoing ‘preventative chemotherapy’ after cancer diagnosis: ‘Stronger every day’

Princess Kate Middleton announced on Friday that she's been diagnosed with cancer following major abdominal surgery in January.

The Princess of Wales has just begun a treatment regimen of "preventative chemotherapy," she said in a video message.

After Middleton underwent "major abdominal surgery" in January, it was initially thought that her condition was "non-cancerous," she said in the video message.

KATE MIDDLETON ANNOUNCES SHE HAS CANCER, UNDERGOING CHEMOTHERAPY TREATMENT

However, later testing revealed that "cancer had been present." 

She did not specify what type of cancer was diagnosed.

Preventative chemotherapy, otherwise known as chemoprevention, is the use of certain drugs to help lower the risk of developing cancer or prevent it from returning, according to the NIH National Cancer Institute (NCI).

These include drugs like tamoxifen and raloxifene, which can be used in the prevention of "certain types of breast cancer in women who are at high risk of developing the disease," the NCI said.

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Dr. Christina Annunziata, senior vice president of extramural discovery science at the American Cancer Society in Virginia, said that preventative chemo is given when the cancer has been removed, but there might be a few "microscopic cells" still remaining.

"There may be a few cells that have already spread and have the ability to regrow the cancer, and this is the purpose of the chemo to be given in this setting," she told Fox News Digital. "The chemo is given to kill these cells and ‘prevent’ the cancer from relapsing or coming back."

Another term for this treatment is "adjuvant chemotherapy,'" she said.

The American Society of Clinical Oncology (ASCO) website states that a doctor will use chemoprevention methods in cases where patients are high risk due to family history or a previous cancer diagnosis. 

Chemoprevention can involve medicines, vitamins or other substances dependent on cancer type, according to City of Hope.

These drugs are not used to treat cancer — and taking them "does not fully protect a person from developing cancer in the future," noted ASCO.

Some of the more common side effects of chemotherapy include hair loss, fatigue, nausea, vomiting, easy bruising and bleeding, appetite changes, weight changes, anemia and gastrointestinal issues.

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The princess on Friday asked for privacy as she focuses on treatment and recovery.

"We hope that you will understand that, as a family, we now need some time, space and privacy while I complete my treatment," she said. 

"I am well and getting stronger every day by focusing on the things that will help me heal, in my mind, body and spirits."

The princess noted that she looks forward to returning to work, but that she now "must focus on making a full recovery."

"At this time, I am also thinking of all those whose lives have been affected by cancer," she added. 

"For everyone facing this disease, in whatever form, please do not lose faith or hope. You are not alone."

Fox News Digital's Lauryn Overhultz contributed to this report.

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Global fertility rates may become too low to sustain population levels, study says

Fertility rates in nearly all countries will be too low to sustain population levels by the end of the century, and most of the world's live births will be occurring in poorer countries, according to a study published on Wednesday.

The trend will lead to a "baby boom" and "baby bust" divide across the world, with the boom concentrated in low-income countries that are more susceptible to economic and political instability, senior researcher Stein Emil Vollset from the Institute for Health Metrics and Evaluation (IHME) at the University of Washington in Seattle said in a statement.

The study reported in The Lancet projects 155 of 204 countries and territories worldwide, or 76%, will have fertility rates below population replacement levels by 2050. By 2100, that is expected to rise to 198, or 97%, researchers estimated.

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The forecasts are based on surveys, censuses, and other sources of data collected from 1950 through 2021 as part of the Global Burden of Diseases, Injuries, and Risk Factors Study.

Over three-quarters of live births will occur in low- and lower-middle-income countries by the end of the century, with more than half taking place in sub-Saharan Africa, researchers said.

The global fertility rate - the average number of births per woman - has fallen from around 5 children in 1950 to 2.2 in 2021, data show.

By 2021, 110 countries and territories (54%) had rates below the population replacement level of 2.1 children per woman.

The study highlights a particularly worrying trend for countries like South Korea and Serbia, where the fertility rate is less than 1.1 child per female, exposing them to challenges of a dwindling workforce.

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Many of the most resource-limited countries "will be grappling with how to support the youngest, fastest-growing population on the planet in some of the most politically and economically unstable, heat-stressed, and health system-strained places on earth," Vollset said.

While tumbling fertility rates in high-income countries reflect more opportunities for education and employment for women, researchers said the trend signals an urgent need for improvement in access to modern contraception and female education in other regions.

In addition, "once nearly every country's population is shrinking, reliance on open immigration will become necessary to sustain economic growth," IHME's Natalia Bhattacharjee, a coauthor of the report, said in a statement.

The authors noted that predictions were limited by quantity and quality of past data, especially for the 2020 to 2021 COVID-19 pandemic period.

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COVID pandemic led to thousands of missed prostate cancer cases, new study finds

Tens of thousands of prostate cancer cases were missed during the disruption of the COVID pandemic.

Those are the findings of a new study published in BJU International last month.

Researchers from the University of Oxford and other U.K. universities analyzed a dataset of 285,160 participants from OpenSAFELY-TPP, a large, nationally representative dataset of routine health care records.

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They focused on 165,410 men in the U.K. who had been diagnosed with prostate cancer between Jan. 2015 and July 2023.

In 2020, diagnoses of prostate cancer dropped by 31% over the prior year.

The decrease was 18% in 2021. 

By 2022, the diagnosed cases had returned to expected levels.

"Given that our dataset represents 40% of the population, we estimate that proportionally the pandemic led to 20,000 missed prostate cancer diagnoses in England alone," the researchers wrote in the study discussion. 

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During that time, the age at the time of diagnosis shifted to older individuals.

"The increase in incidence recorded in 2023 was not enough to account for the missed cases," the researchers also stated — which means the diagnoses have not yet "caught up" to those that flew under the radar in 2020 and 2021.

Based on these findings, the researchers are recommending that health care providers focus on finding the men who were affected. 

"More research is needed to investigate the consequences of this on patients and health care systems," they noted.

Dr. Marc Siegel, clinical professor of medicine at NYU Langone Medical Center and a Fox News medical contributor, pointed out that there is no universal screening program in the U.K. for prostate cancer.

"That’s because the feeling is that the PSA [prostate-specific antigen] may be inaccurate," said Siegel, who was not involved in the new U.K. study. 

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"I disagree with that, because most of us here in the U.S. (primary care docs and urologists) follow trends in the PSA, knowing it isn't perfect but using it as a guide to something going on in the prostate."

The PSA is a blood test that measures the level of a specific protein that is made by the prostate.

"In the U.K., there is currently a massive ongoing study on the effectiveness of different kinds of screening modalities for prostate cancer, but in the U.S., many major medical centers — including mine — have already integrated the latest MRI tests to look at patients with high PSA or increasing trends prior to prostate biopsy," Siegel told Fox News Digital.

"The MRI also allows you to target the biopsy to a certain area of abnormality when needed."

Regarding the effects of the pandemic, Siegel noted that lockdowns led to a delay in routine medical care both in the U.S. and in the U.K.

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"The delayed diagnoses in the U.K. are not surprising," he added.

The study did have some limitations, the researchers acknowledged.

First, it focused only on data from England — so it does not apply to global populations.

It is also possible that some cases were missed, as the diagnoses were pulled from primary care health records rather than cancer registries.

"However, in the U.K., the information about cancer diagnosis is sent to primary care within the hospital discharge letters and primary care is a valid source of these data," the researchers stated.

"We validated the results against other published studies, and they closely align, confirming the validity of the methodology."

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The study doesn’t prove that COVID caused the dip in diagnoses, the researchers noted — as it’s possible there are "multiple explanatory factors not limited to the COVID-19 pandemic."

But the study did note that "during the COVID-19 pandemic, the resources, and the attention in healthcare systems globally, shifted toward preventing and managing COVID-19. Access to the non-COVID-19-related healthcare services changed, waiting times increased, and cancer pathways including treatment standards were adapted."

It also said, in part, that "patients’ healthcare-seeking behavior changed as people adopted social distancing (limiting face-to-face contact) and shielding (safeguarding high-risk people) to protect themselves and others from an infection."

Fox News Digital reached out to the study authors for additional comment.

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